diff --git a/src/plugins/ucx/ucx_backend.cpp b/src/plugins/ucx/ucx_backend.cpp
index 57b808f54..4dbc4fd78 100644
--- a/src/plugins/ucx/ucx_backend.cpp
+++ b/src/plugins/ucx/ucx_backend.cpp
@@ -1248,6 +1248,8 @@ nixl_status_t nixlUcxEngine::loadRemoteConnInfo (const std::string &remote_agent
 
     remoteConnMap.insert({remote_agent, conn});
 
+    performConnectionEstablishment(remote_agent, conn);
+
     return NIXL_SUCCESS;
 }
 
@@ -1817,3 +1819,33 @@ nixl_status_t nixlUcxEngine::genNotif(const std::string &remote_agent, const std
     }
     return NIXL_SUCCESS;
 }
+
+void
+nixlUcxEngine::performConnectionEstablishment(
+    const std::string &remote_agent,
+    const std::shared_ptr<nixlUcxConnection> &conn) const {
+    NIXL_DEBUG << "Establishing connection with " << remote_agent;
+
+    // Flush all endpoints to ensure connection establishment
+    // and avoid UCS_ERR_NOT_CONNECTED errors during data transfers
+    for (size_t i = 0; i < conn->eps.size(); ++i) {
+        nixlUcxReq req;
+        nixl_status_t ret = conn->eps[i]->flushEp(req);
+
+        if (ret == NIXL_IN_PROG) {
+            nixlUcxWorker *worker = getWorker(i).get();
+            do {
+                ret = worker->test(req);
+            } while (ret == NIXL_IN_PROG);
+
+            worker->reqRelease(req);
+        }
+
+        if (ret != NIXL_SUCCESS) {
+            NIXL_WARN << "Failed to flush endpoint " << i << " for " << remote_agent
+                      << ", status: " << ret;
+        }
+    }
+
+    NIXL_DEBUG << "Connection establishment completed for " << remote_agent;
+}
diff --git a/src/plugins/ucx/ucx_backend.h b/src/plugins/ucx/ucx_backend.h
index 51d5ec423..569b38a89 100644
--- a/src/plugins/ucx/ucx_backend.h
+++ b/src/plugins/ucx/ucx_backend.h
@@ -287,6 +287,10 @@ class nixlUcxEngine : public nixlBackendEngine {
     ucx_connection_ptr_t
     getConnection(const std::string &remote_agent) const;
 
+    void
+    performConnectionEstablishment(const std::string &remote_agent,
+                                   const std::shared_ptr<nixlUcxConnection> &conn) const;
+
     /* UCX data */
     std::unique_ptr<nixlUcxContext> uc;
     std::vector<std::unique_ptr<nixlUcxWorker>> uws;
diff --git a/test/gtest/device_api/single_write_test.cu b/test/gtest/device_api/single_write_test.cu
index 086d1547f..33b711671 100644
--- a/test/gtest/device_api/single_write_test.cu
+++ b/test/gtest/device_api/single_write_test.cu
@@ -194,19 +194,6 @@ protected:
         agent.registerMem(reg_list);
     }
 
-    void
-    completeWireup(size_t from_agent, size_t to_agent) {
-        nixl_notifs_t notifs;
-        nixl_status_t status = getAgent(from_agent).genNotif(getAgentName(to_agent), NOTIF_MSG);
-        ASSERT_EQ(status, NIXL_SUCCESS) << "Failed to complete wireup";
-
-        do {
-            nixl_status_t ret = getAgent(to_agent).getNotifs(notifs);
-            ASSERT_EQ(ret, NIXL_SUCCESS) << "Failed to get notifications during wireup";
-            std::this_thread::sleep_for(std::chrono::milliseconds(10));
-        } while (notifs.size() == 0);
-    }
-
     void
     exchangeMD(size_t from_agent, size_t to_agent) {
         for (size_t i = 0; i < agents.size(); i++) {
@@ -222,8 +209,6 @@ protected:
                 EXPECT_EQ(remote_agent_name, getAgentName(i));
             }
         }
-
-        completeWireup(from_agent, to_agent);
     }
 
     void
diff --git a/test/gtest/device_api/utils.cu b/test/gtest/device_api/utils.cu
index acbc60313..bb1513b6e 100644
--- a/test/gtest/device_api/utils.cu
+++ b/test/gtest/device_api/utils.cu
@@ -100,18 +100,6 @@ void DeviceApiTestBase::registerMem(nixlAgent &agent, const std::vector<MemBuffe
     agent.registerMem(reg_list);
 }
 
-void DeviceApiTestBase::completeWireup(size_t from_agent, size_t to_agent) {
-    nixl_notifs_t notifs;
-    nixl_status_t status = getAgent(from_agent).genNotif(getAgentName(to_agent), NOTIF_MSG);
-    ASSERT_EQ(status, NIXL_SUCCESS) << "Failed to complete wireup";
-
-    do {
-        nixl_status_t ret = getAgent(to_agent).getNotifs(notifs);
-        ASSERT_EQ(ret, NIXL_SUCCESS) << "Failed to get notifications during wireup";
-        std::this_thread::sleep_for(std::chrono::milliseconds(10));
-    } while (notifs.size() == 0);
-}
-
 void DeviceApiTestBase::exchangeMD(size_t from_agent, size_t to_agent) {
     for (size_t i = 0; i < agents.size(); i++) {
         nixl_blob_t md;
@@ -126,8 +114,6 @@ void DeviceApiTestBase::exchangeMD(size_t from_agent, size_t to_agent) {
             EXPECT_EQ(remote_agent_name, getAgentName(i));
         }
     }
-
-    completeWireup(from_agent, to_agent);
 }
 
 void DeviceApiTestBase::invalidateMD() {
diff --git a/test/gtest/device_api/utils.cuh b/test/gtest/device_api/utils.cuh
index 9f3489980..7eff87565 100644
--- a/test/gtest/device_api/utils.cuh
+++ b/test/gtest/device_api/utils.cuh
@@ -139,7 +139,7 @@ protected:
     nixlDescList<Desc> makeDescList(const std::vector<MemBuffer> &buffers, nixl_mem_t mem_type);
 
     void registerMem(nixlAgent &agent, const std::vector<MemBuffer> &buffers, nixl_mem_t mem_type);
-    void completeWireup(size_t from_agent, size_t to_agent);
+
     void exchangeMD(size_t from_agent, size_t to_agent);
     void invalidateMD();