diff --git a/packages/common/src/eips.ts b/packages/common/src/eips.ts
index 42a2933f015..d2abacef501 100644
--- a/packages/common/src/eips.ts
+++ b/packages/common/src/eips.ts
@@ -521,4 +521,13 @@ export const eipsDict: EIPsDict = {
     minimumHardfork: Hardfork.Chainstart,
     requiredEIPs: [],
   },
+  /**
+   * Description : Precompile for secp256r1 Curve Support
+   * URL         : https://eips.ethereum.org/EIPS/eip-7951
+   * Status      : Draft
+   */
+  7951: {
+    minimumHardfork: Hardfork.Chainstart,
+    requiredEIPs: [],
+  },
 }
diff --git a/packages/common/src/hardforks.ts b/packages/common/src/hardforks.ts
index c60a771829d..6651c6577ed 100644
--- a/packages/common/src/hardforks.ts
+++ b/packages/common/src/hardforks.ts
@@ -166,7 +166,7 @@ export const hardforksDict: HardforksDict = {
    * Status     : Draft
    */
   osaka: {
-    eips: [7594, 7823, 7825, 7883, 7939],
+    eips: [7594, 7823, 7825, 7883, 7939, 7951],
   },
   /**
    * Description: Next feature hardfork after osaka, internally used for verkle testing/implementation (incomplete/experimental)
diff --git a/packages/evm/src/evm.ts b/packages/evm/src/evm.ts
index 25134bee3f2..915dc1b99bd 100644
--- a/packages/evm/src/evm.ts
+++ b/packages/evm/src/evm.ts
@@ -257,7 +257,7 @@ export class EVM implements EVMInterface {
       663, 1153, 1559, 2537, 2565, 2718, 2929, 2930, 2935, 3198, 3529, 3540, 3541, 3607, 3651, 3670,
       3855, 3860, 4200, 4399, 4750, 4788, 4844, 4895, 5133, 5450, 5656, 6110, 6206, 6780, 6800,
       7002, 7069, 7251, 7480, 7516, 7594, 7620, 7685, 7691, 7692, 7698, 7702, 7709, 7823, 7825,
-      7939,
+      7939, 7951,
     ]
 
     for (const eip of this.common.eips()) {
diff --git a/packages/evm/src/precompiles/100-p256verify.ts b/packages/evm/src/precompiles/100-p256verify.ts
new file mode 100644
index 00000000000..0aaf7acc109
--- /dev/null
+++ b/packages/evm/src/precompiles/100-p256verify.ts
@@ -0,0 +1,149 @@
+import { bytesToBigInt, bytesToHex, setLengthLeft } from '@ethereumjs/util'
+import { p256 } from '@noble/curves/p256'
+
+import { OOGResult } from '../evm.ts'
+
+import { getPrecompileName } from './index.ts'
+import type { PrecompileInput } from './types.ts'
+import { gasLimitCheck } from './util.ts'
+
+import type { ExecResult } from '../types.ts'
+
+const P256VERIFY_GAS_COST = BigInt(6900)
+const SUCCESS_RETURN = new Uint8Array(32).fill(0).map((_, i) => (i === 31 ? 1 : 0))
+
+// Curve parameters for secp256r1
+const P256_N = BigInt('0xffffffff00000000ffffffffffffffffbce6faada7179e84f3b9cac2fc632551') // Subgroup order
+const P256_P = BigInt('0xffffffff00000001000000000000000000000000ffffffffffffffffffffffff') // Base field modulus
+const P256_A = BigInt('0xffffffff00000001000000000000000000000000fffffffffffffffffffffffc') // Curve coefficient a
+const P256_B = BigInt('0x5ac635d8aa3a93e7b3ebbd55769886bc651d06b0cc53b0f63bce3c3e27d2604b') // Curve coefficient b
+
+export function precompile100(opts: PrecompileInput): ExecResult {
+  const pName = getPrecompileName('100')
+  const gasUsed = P256VERIFY_GAS_COST
+
+  if (!gasLimitCheck(opts, gasUsed, pName)) {
+    return OOGResult(opts.gasLimit)
+  }
+
+  const data = opts.data
+
+  // 1. Input length: Input MUST be exactly 160 bytes
+  if (data.length !== 160) {
+    if (opts._debug !== undefined) {
+      opts._debug(`${pName} failed: invalid input length ${data.length}, expected 160`)
+    }
+    return {
+      executionGasUsed: gasUsed,
+      returnValue: new Uint8Array(),
+    }
+  }
+
+  const msgHash = data.subarray(0, 32)
+  const r = data.subarray(32, 64)
+  const s = data.subarray(64, 96)
+  const qx = data.subarray(96, 128)
+  const qy = data.subarray(128, 160)
+
+  const rBigInt = bytesToBigInt(r)
+  const sBigInt = bytesToBigInt(s)
+  const qxBigInt = bytesToBigInt(qx)
+  const qyBigInt = bytesToBigInt(qy)
+
+  // 2. Signature component bounds: Both r and s MUST satisfy 0 < r < n and 0 < s < n
+  if (!(rBigInt > BigInt(0) && rBigInt < P256_N && sBigInt > BigInt(0) && sBigInt < P256_N)) {
+    if (opts._debug !== undefined) {
+      opts._debug(
+        `${pName} failed: signature component out of bounds: r=${bytesToHex(r)}, s=${bytesToHex(s)}`,
+      )
+    }
+    return {
+      executionGasUsed: gasUsed,
+      returnValue: new Uint8Array(),
+    }
+  }
+
+  // 3. Public key bounds: Both qx and qy MUST satisfy 0 ≤ qx < p and 0 ≤ qy < p
+  if (!(qxBigInt >= BigInt(0) && qxBigInt < P256_P && qyBigInt >= BigInt(0) && qyBigInt < P256_P)) {
+    if (opts._debug !== undefined) {
+      opts._debug(
+        `${pName} failed: public key component out of bounds: qx=${bytesToHex(qx)}, qy=${bytesToHex(qy)}`,
+      )
+    }
+    return {
+      executionGasUsed: gasUsed,
+      returnValue: new Uint8Array(),
+    }
+  }
+
+  // 4. Point validity: The point (qx, qy) MUST satisfy the curve equation qy^2 ≡ qx^3 + a*qx + b (mod p)
+  const leftSide = (qyBigInt * qyBigInt) % P256_P
+  const rightSide = (qxBigInt * qxBigInt * qxBigInt + P256_A * qxBigInt + P256_B) % P256_P
+
+  if (leftSide !== rightSide) {
+    if (opts._debug !== undefined) {
+      opts._debug(`${pName} failed: point not on curve`)
+    }
+    return {
+      executionGasUsed: gasUsed,
+      returnValue: new Uint8Array(),
+    }
+  }
+
+  // 5. Point not at infinity: The point (qx, qy) MUST NOT be the point at infinity (represented as (0, 0))
+  if (qxBigInt === BigInt(0) && qyBigInt === BigInt(0)) {
+    if (opts._debug !== undefined) {
+      opts._debug(`${pName} failed: public key is point at infinity`)
+    }
+    return {
+      executionGasUsed: gasUsed,
+      returnValue: new Uint8Array(),
+    }
+  }
+
+  try {
+    // Create public key point
+    const publicKey = p256.ProjectivePoint.fromAffine({
+      x: qxBigInt,
+      y: qyBigInt,
+    })
+
+    // Create signature
+    const rBytes = setLengthLeft(r, 32)
+    const sBytes = setLengthLeft(s, 32)
+    const signatureBytes = new Uint8Array(64)
+    signatureBytes.set(rBytes, 0)
+    signatureBytes.set(sBytes, 32)
+
+    const signature = p256.Signature.fromCompact(signatureBytes)
+
+    // Verify signature
+    const isValid = p256.verify(signature, msgHash, publicKey.toRawBytes(false))
+
+    if (isValid) {
+      if (opts._debug !== undefined) {
+        opts._debug(`${pName} succeeded: signature verification passed`)
+      }
+      return {
+        executionGasUsed: gasUsed,
+        returnValue: SUCCESS_RETURN,
+      }
+    } else {
+      if (opts._debug !== undefined) {
+        opts._debug(`${pName} failed: signature verification failed`)
+      }
+      return {
+        executionGasUsed: gasUsed,
+        returnValue: new Uint8Array(),
+      }
+    }
+  } catch (error) {
+    if (opts._debug !== undefined) {
+      opts._debug(`${pName} failed: verification error: ${error}`)
+    }
+    return {
+      executionGasUsed: gasUsed,
+      returnValue: new Uint8Array(),
+    }
+  }
+}
diff --git a/packages/evm/src/precompiles/index.ts b/packages/evm/src/precompiles/index.ts
index 1d2ac3605d6..4cc47f56616 100644
--- a/packages/evm/src/precompiles/index.ts
+++ b/packages/evm/src/precompiles/index.ts
@@ -18,6 +18,7 @@ import { precompile08 } from './08-bn254-pairing.ts'
 import { precompile09 } from './09-blake2f.ts'
 import { precompile10 } from './10-bls12-map-fp-to-g1.ts'
 import { precompile11 } from './11-bls12-map-fp2-to-g2.ts'
+import { precompile100 } from './100-p256verify.ts'
 import { MCLBLS, NobleBLS } from './bls12_381/index.ts'
 import { NobleBN254, RustBN254 } from './bn254/index.ts'
 
@@ -213,6 +214,15 @@ const precompileEntries: PrecompileEntry[] = [
     precompile: precompile11,
     name: 'BLS12_MAP_FP_TO_G2 (0x11)',
   },
+  {
+    address: '0000000000000000000000000000000000000100',
+    check: {
+      type: PrecompileAvailabilityCheck.EIP,
+      param: 7951,
+    },
+    precompile: precompile100,
+    name: 'P256VERIFY (0x100)',
+  },
 ]
 
 const precompiles: Precompiles = {
@@ -233,6 +243,7 @@ const precompiles: Precompiles = {
   [BYTES_19 + '0f']: precompile0f,
   [BYTES_19 + '10']: precompile10,
   [BYTES_19 + '11']: precompile11,
+  '0000000000000000000000000000000000000100': precompile100,
 }
 
 type DeletePrecompile = {
diff --git a/packages/evm/test/precompiles/100-p256verify.spec.ts b/packages/evm/test/precompiles/100-p256verify.spec.ts
new file mode 100644
index 00000000000..88204caa529
--- /dev/null
+++ b/packages/evm/test/precompiles/100-p256verify.spec.ts
@@ -0,0 +1,164 @@
+import { Common, Mainnet } from '@ethereumjs/common'
+import { Address, hexToBytes } from '@ethereumjs/util'
+import { p256 } from '@noble/curves/p256'
+import { assert, beforeAll, describe, it } from 'vitest'
+
+import { createEVM } from '../../src/index.ts'
+import { precompile100 } from '../../src/precompiles/100-p256verify.ts'
+
+import type { PrecompileInput } from '../../src/precompiles/types.ts'
+
+const testCases = [
+  {
+    name: 'valid signature verification',
+    input: (() => {
+      // Generate a test key pair and signature
+      const privateKey = p256.utils.randomPrivateKey()
+      const publicKey = p256.getPublicKey(privateKey, false) // Get uncompressed public key
+      const message = new Uint8Array(32)
+      message[31] = 1 // Simple test message
+
+      const signature = p256.sign(message, privateKey)
+      const signatureBytes = signature.toCompactRawBytes()
+
+      // Format input: msgHash (32) + r (32) + s (32) + qx (32) + qy (32)
+      const input = new Uint8Array(160)
+      input.set(message, 0) // msgHash
+      input.set(signatureBytes.slice(0, 32), 32) // r
+      input.set(signatureBytes.slice(32, 64), 64) // s
+      input.set(publicKey.slice(1, 33), 96) // qx (uncompressed public key)
+      input.set(publicKey.slice(33, 65), 128) // qy
+
+      return input
+    })(),
+    expectedReturn: new Uint8Array(32).fill(0).map((_, i) => (i === 31 ? 1 : 0)), // Success
+    expectedGasUsed: BigInt(6900),
+  },
+  {
+    name: 'invalid input length',
+    input: new Uint8Array(159), // Wrong length
+    expectedReturn: new Uint8Array(0), // Failure
+    expectedGasUsed: BigInt(6900),
+  },
+  {
+    name: 'invalid signature - r out of bounds',
+    input: (() => {
+      const input = new Uint8Array(160)
+      // Set r to curve order (invalid)
+      const r = hexToBytes('0xffffffff00000000ffffffffffffffffbce6faada7179e84f3b9cac2fc632551')
+      input.set(r, 32)
+      return input
+    })(),
+    expectedReturn: new Uint8Array(0), // Failure
+    expectedGasUsed: BigInt(6900),
+  },
+  {
+    name: 'invalid signature - s out of bounds',
+    input: (() => {
+      const input = new Uint8Array(160)
+      // Set s to curve order (invalid)
+      const s = hexToBytes('0xffffffff00000000ffffffffffffffffbce6faada7179e84f3b9cac2fc632551')
+      input.set(s, 64)
+      return input
+    })(),
+    expectedReturn: new Uint8Array(0), // Failure
+    expectedGasUsed: BigInt(6900),
+  },
+  {
+    name: 'invalid public key - point not on curve',
+    input: (() => {
+      const input = new Uint8Array(160)
+      // Set invalid public key coordinates
+      input.set(new Uint8Array(32).fill(1), 96) // qx
+      input.set(new Uint8Array(32).fill(2), 128) // qy
+      return input
+    })(),
+    expectedReturn: new Uint8Array(0), // Failure
+    expectedGasUsed: BigInt(6900),
+  },
+  {
+    name: 'invalid public key - point at infinity',
+    input: (() => {
+      const input = new Uint8Array(160)
+      // Set point at infinity (0, 0)
+      input.set(new Uint8Array(32), 96) // qx = 0
+      input.set(new Uint8Array(32), 128) // qy = 0
+      return input
+    })(),
+    expectedReturn: new Uint8Array(0), // Failure
+    expectedGasUsed: BigInt(6900),
+  },
+  {
+    name: 'invalid signature verification',
+    input: (() => {
+      // Generate a valid key pair but wrong signature
+      const privateKey = p256.utils.randomPrivateKey()
+      const publicKey = p256.getPublicKey(privateKey, false) // Get uncompressed public key
+      const message = new Uint8Array(32)
+      message[31] = 1
+
+      // Use wrong message for signature
+      const wrongMessage = new Uint8Array(32)
+      wrongMessage[31] = 2
+      const signature = p256.sign(wrongMessage, privateKey)
+      const signatureBytes = signature.toCompactRawBytes()
+
+      const input = new Uint8Array(160)
+      input.set(message, 0) // msgHash (different from signed message)
+      input.set(signatureBytes.slice(0, 32), 32) // r
+      input.set(signatureBytes.slice(32, 64), 64) // s
+      input.set(publicKey.slice(1, 33), 96) // qx
+      input.set(publicKey.slice(33, 65), 128) // qy
+
+      return input
+    })(),
+    expectedReturn: new Uint8Array(0), // Failure
+    expectedGasUsed: BigInt(6900),
+  },
+]
+
+describe('P256VERIFY precompile', () => {
+  let common: Common
+  let evm: any
+
+  beforeAll(async () => {
+    common = new Common({ chain: Mainnet, eips: [7951] })
+    evm = await createEVM({ common })
+  })
+
+  describe('precompile100', () => {
+    for (const testCase of testCases) {
+      it(`should handle ${testCase.name}`, () => {
+        const opts: PrecompileInput = {
+          data: testCase.input,
+          gasLimit: BigInt(10000),
+          common,
+          _EVM: evm,
+        }
+
+        const result = precompile100(opts)
+
+        assert.equal(result.executionGasUsed, testCase.expectedGasUsed)
+        assert.deepEqual(result.returnValue, testCase.expectedReturn)
+      })
+    }
+  })
+
+  describe('integration with EVM', () => {
+    it('should be callable from EVM', async () => {
+      // Create a simple contract that calls the P256VERIFY precompile
+      const code = hexToBytes(
+        '0x6101006000526001601f600060003660006000610100611af4f13d6001556000553d600060003e3d600020600255',
+      )
+
+      const result = await evm.runCall({
+        to: undefined, // Contract creation
+        caller: new Address(hexToBytes('0x0000000000000000000000000000000000000000')),
+        data: code,
+        gasLimit: BigInt(100000),
+      })
+
+      assert.equal(result.execResult.exceptionError, undefined)
+    })
+  })
+})