reduce percentage of greedy mutations

martinpacesa · web-flow · commit 05702c435e21 · 2025-06-30T12:27:29.000+02:00
diff --git a/settings_advanced/betasheet_4stage_multimer.json b/settings_advanced/betasheet_4stage_multimer.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_flexible.json b/settings_advanced/betasheet_4stage_multimer_flexible.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_flexible_hardtarget.json b/settings_advanced/betasheet_4stage_multimer_flexible_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_hardtarget.json b/settings_advanced/betasheet_4stage_multimer_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_mpnn.json b/settings_advanced/betasheet_4stage_multimer_mpnn.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_mpnn_flexible.json b/settings_advanced/betasheet_4stage_multimer_mpnn_flexible.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_mpnn_flexible_hardtarget.json b/settings_advanced/betasheet_4stage_multimer_mpnn_flexible_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/betasheet_4stage_multimer_mpnn_hardtarget.json b/settings_advanced/betasheet_4stage_multimer_mpnn_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.15,
diff --git a/settings_advanced/default_4stage_multimer.json b/settings_advanced/default_4stage_multimer.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_flexible.json b/settings_advanced/default_4stage_multimer_flexible.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_flexible_hardtarget.json b/settings_advanced/default_4stage_multimer_flexible_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_hardtarget.json b/settings_advanced/default_4stage_multimer_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_mpnn.json b/settings_advanced/default_4stage_multimer_mpnn.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_mpnn_flexible.json b/settings_advanced/default_4stage_multimer_mpnn_flexible.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_mpnn_flexible_hardtarget.json b/settings_advanced/default_4stage_multimer_mpnn_flexible_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
diff --git a/settings_advanced/default_4stage_multimer_mpnn_hardtarget.json b/settings_advanced/default_4stage_multimer_mpnn_hardtarget.json
@@ -14,7 +14,7 @@
     "temporary_iterations": 45,
     "hard_iterations": 5,
     "greedy_iterations": 15,
-    "greedy_percentage": 5,
+    "greedy_percentage": 1,
     "save_design_animations": true,
     "save_design_trajectory_plots": true,
     "weights_plddt": 0.1,
